Seresto provides continuous release of imidacloprid and flumethrin through the collar material for 8 months. It's the longest-duration OTC flea and tick prevention available and costs less per month than monthly topical treatments.
Imidacloprid (kills fleas) and flumethrin (kills ticks) are embedded in a polymer matrix that continuously releases active ingredients through the collar surface, spreading across the dog's coat via natural oils. The contact-kill mechanism means ticks die without biting — preventing transmission of Lyme disease (which requires 24-48 hour tick attachment).
Flumethrin is toxic to cats. In multi-pet households where cats groom the dog wearing Seresto, switch to Frontline Plus or NexGard (oral, no surface residue). Never use Seresto on cats — it's formulated only for dogs.
Dogs who need year-round flea and tick prevention without monthly topical applications.
Dogs with skin sensitivities at the collar site, or dogs living with cats who might groom the collar (flumethrin is toxic to cats).
The best value flea and tick option for dog-only households. Multi-pet households with cats: use oral NexGard instead.
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